Glucosamine and Horses!


Glucosamine is the most widely researched of the many joint support ingredients referred to as “nutraceuticals”, it is a water-soluble amino monosaccharide that is the fundamental building block for articular cartilage. It is derived from the hydrolysis of crustacean exoskeletons which produce chitin. Glucosamine is the precursor for stimulating the major structural components of joint cartilage called glycosaminoglycans (GAG’s), hyaluronate, collagen, chondroitin and keratin sulfates. Glucosamine, is safe and will not affect insulin resistant horses. Glucosamine serves a dual purpose by supporting the horse’s ability to neutralize the destructive free radicals and enzymes that can break down cartilage and then supplying nutrients to the cartilage cells (chondrocytes) and helping the transport of waste products away from the cartilage. Glucosamine is available as glucosamine hydrochloride HCL or Glucosamine Sulfate. Glucosamine HCL is the most efficient form with a bioavailability of 98% through the stomach and subsequently to various biosynthetic pathways, which includes synthesis of cartilage and GAG’s. Glucosamine Sulfate contains only 50-60% active glucosamine and the remainder are sulfur salts.


Thank you to Grand Meadows for sharing their knowledge about joint supplements!  Many of their formulas, including Grand Premium Plus and Grand Flex contain the suggested daily dose of glucosamine.